GLP-1 Evidence

Not medical advice. A record of published research and our assessments of it. The limits

Which GLP-1 drug is which

Ozempic, Wegovy and Rybelsus are all semaglutide. Mounjaro and Zepbound are both tirzepatide. Studies are usually reported by molecule, not brand, so this page maps each brand sold in the United States to its molecule, says what its current label covers, and links to the studies of that molecule in this collection.

Each row rests on the manufacturer's current label as published on DailyMed, read 25 September 2026. Uses are summarized; the label is the authority. Brand names belong to their manufacturers. Not medical advice.

01Approved

FDA-approved GLP-1 drugs, by molecule

Semaglutide

GLP-1 receptor agonist · 110 studies in this collection

Brand and makerFormWhat the US label says it is for
Ozempic injection
Novo Nordisk
Injection, once weeklyType 2 diabetes. Also lowers the risk of heart attack, stroke and cardiovascular death in type 2 diabetes with established heart disease, and of kidney decline, kidney failure and cardiovascular death in type 2 diabetes with chronic kidney disease. Label
Ozempic tablets and Rybelsus
Novo Nordisk
Tablet, once dailyType 2 diabetes. Also lowers the risk of heart attack, stroke and cardiovascular death in type 2 diabetes at high risk of these events. One label covers both names. Label
Wegovy injection
Novo Nordisk
Injection, once weeklyWeight management in adults, and in children 12 and older with obesity. Also lowers the risk of heart attack, stroke and cardiovascular death in adults with heart disease and obesity or overweight, and treats MASH with moderate to advanced liver fibrosis (accelerated approval). Label
Wegovy tablets
Novo Nordisk
Tablet, once dailyWeight management in adults. Also lowers the risk of heart attack, stroke and cardiovascular death in adults with heart disease and obesity or overweight. Label

Tirzepatide

GIP and GLP-1 receptor agonist · 58 studies in this collection

Brand and makerFormWhat the US label says it is for
Mounjaro
Eli Lilly
Injection, once weeklyType 2 diabetes in adults and children 10 and older. Also lowers the risk of heart attack, stroke and cardiovascular death in type 2 diabetes at high risk of these events. Label
Zepbound
Eli Lilly
Injection, once weeklyWeight management in adults. Also treats moderate to severe obstructive sleep apnea in adults with obesity. Label

Orforglipron

GLP-1 receptor agonist · 4 studies in this collection

Brand and makerFormWhat the US label says it is for
Foundayo
Eli Lilly
Tablet, once dailyWeight management in adults. Approved 1 April 2026. Label

Liraglutide

GLP-1 receptor agonist · 69 studies in this collection

Brand and makerFormWhat the US label says it is for
Victoza
Novo Nordisk
Injection, once dailyType 2 diabetes in adults and children 10 and older. Also lowers the risk of heart attack, stroke and cardiovascular death in type 2 diabetes with established heart disease. Label
Saxenda
Novo Nordisk
Injection, once dailyWeight management in adults, and in children 12 and older who weigh more than 60 kg and have obesity. Label
Xultophy 100/3.6
Novo Nordisk
Injection, combined with insulin degludecType 2 diabetes in adults. Label

Generic liraglutide injection is also sold: DailyMed lists labels from several generic manufacturers.

Dulaglutide

GLP-1 receptor agonist · 27 studies in this collection

Brand and makerFormWhat the US label says it is for
Trulicity
Eli Lilly
Injection, once weeklyType 2 diabetes in adults and children 10 and older. Also lowers the risk of heart attack, stroke and cardiovascular death in type 2 diabetes with heart disease or multiple risk factors. Label

Exenatide

GLP-1 receptor agonist · 35 studies in this collection

Brand and makerFormWhat the US label says it is for
Byetta
AstraZeneca
Injection, twice dailyType 2 diabetes in adults. Label

DailyMed shows no current label for Bydureon BCise, the once-weekly form.

Lixisenatide

GLP-1 receptor agonist · 7 studies in this collection

Brand and makerFormWhat the US label says it is for
Soliqua 100/33
Sanofi
Injection, combined with insulin glargineType 2 diabetes in adults. Label

DailyMed shows no current label for Adlyxin, the stand-alone form.

The two semaglutide tablets are not interchangeable with each other by dose. Their shared label says: “RYBELSUS and OZEMPIC tablets are not substitutable on a mg-to-mg basis.”

02Not approved

Studied here, not FDA-approved

These appear in the studies and trials here but are not approved in the United States. None appears on FDA's Novel Drug Approvals for 2026 page, current as of 14 September 2026. A product sold under one of these names is not an approved drug.

03Compounded

Compounded semaglutide and tirzepatide

Compounded versions are made by pharmacies, not by the manufacturers above, and are not FDA-approved. FDA's page on unapproved GLP-1 drugs says: “This means the agency does not review compounded drugs for safety, effectiveness or quality before they are marketed.” FDA's page. The Enforcement page records regulatory and court actions against sellers.