GLP-1 Evidence

Not medical advice. A record of published research and our assessments of it. The limits

Effect of GLP1 Receptor Agonists on Physical Function, Body Composition, and Markers of Aging in Older Adults

Status
CompletedResults posted
Why it is watched
non-weight indication: lean_mass, aging
Who it enrolls
age 65 Years to 90 Years; BMI ≥27 required; conditions: Aging; Diabetes Mellitus, Type 2; PreDiabetes; Overweight and Obesity
Interventions
Semaglutide Injectable Product; Lifestyle Counseling
Conditions
Aging; Diabetes Mellitus, Type 2; PreDiabetes; Overweight and Obesity
Phase and size
Phase 4 · 20 participants
Dates
Start 2023-04-01
Primary completion 2024-05-20
Sponsor
The University of Texas Health Science Center at San Antonio (Other)
Last checked
Sep 13, 2026
01Endpoints

What the trial will measure

  • Lean Body Mass ChangeBaseline to 20 weeks
02Eligibility

Who can take part

Inclusion Criteria: * Older than 65 * Have prediabetes or diabetes * BMI ≥ 27.0 kg/m2 * Living independently (not in assisted living or nursing home) Exclusion Criteria: * Have heart disease * Have liver disease * Smoke
03Change log

Registry changes

No changes recorded since the trial was added.