GLP-1 Evidence

Not medical advice. A record of published research and our assessments of it. The limits

Obesity Management for Kidney TRANSPLANTation: OK-TRANSPLANT 2

Status
RecruitingResults none
Why it is watched
non-weight indication: kidney
Who it enrolls
age 18 Years to no upper limit; excludes diabetes; no BMI minimum stated; conditions: Obesity; Chronic Kidney Disease
Interventions
Semaglutide; Virtual Weight Management Coaching
Conditions
Obesity; Chronic Kidney Disease
Phase and size
Phase 4 · 60 participants
Dates
Start 2024-09-26
Primary completion 2026-09-30
Sponsor
Western University, Canada (Other)
Last checked
Sep 13, 2026
01Endpoints

What the trial will measure

  • Feasibility of Recruitment12 months
02Eligibility

Who can take part

Inclusion Criteria: * Adults aged 18 years or older * BMI; 35 kg/m\^2 * 10% risk of ESKD requiring renal replacement therapy over 2 years or receiving dialysis Exclusion Criteria: * Known contraindication to a GLP-1RA (pancreatitis, personal or family history of medullary thyroid cancer, hypersensitivity) * Type 1 diabetes * No access to semaglutide via drug coverage * Pregnant, breastfeeding or planning to become pregnant * Currently in a GLP-1RA or GLP-1RA/GIP study or planning to be in one
03Change log

Registry changes

No changes recorded since the trial was added.