GLP-1 Evidence

Not medical advice. A record of published research and our assessments of it. The limits

The Role of Glucagon-Like Peptide-1 Receptor Agonists in Coronary Artery Diseases and Their Potential Mechanisms

Status
Not yet recruitingResults none
Why it is watched
non-weight indication: cardiovascular
Who it enrolls
age 20 Years to no upper limit; no BMI minimum stated; conditions: Glucagon-Like Peptide-1 Receptor Agonists; Type 2 Diabetes; Coronary Arterial Disease (CAD)
Interventions
Semaglutide 1.0 mg; Semaglutide 0.5 mg
Conditions
Glucagon-Like Peptide-1 Receptor Agonists; Type 2 Diabetes; Coronary Arterial Disease (CAD)
Phase and size
Phase 4 · 60 participants
Dates
Start 2025-10-01
Primary completion 2028-07-31
Sponsor
Taipei Veterans General Hospital, Taiwan (Other gov)
Last checked
Sep 13, 2026
01Endpoints

What the trial will measure

  • change of Time-in-range (%)From enrollment to the end of treatment at 24 weeks
  • change of HbA1cFrom enrollment to the end of treatment at 24 weeks
  • change of Flow-Mediated Dilatation (FMD)From enrollment to the end of treatment at 24 weeks
02Eligibility

Who can take part

Inclusion Criteria: 1. adults (\>=20 years old), 2. Type 2 Diabetes with coronary arterial disease underwent angioplasty within 3 months with SGLT2 inhibitors - Exclusion Criteria: 1. age\<20 years old, 2. pregnant women, 3. eGFR\<30 ml/min/1.73m2, 4. received GLP-1 agonist in the recent 3 months -
03Change log

Registry changes

No changes recorded since the trial was added.